Instructions for AIMOVIG^® SureClick^® autoinjector use (70 mg/mL)

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Guide to parts

Before use

After use

Important: Needle is inside the green safety guard.

Important

Before you use AIMOVIG SureClick autoinjector, read this important information:

Storing your AIMOVIG SureClick autoinjector

Keep the autoinjector out of the reach of children.
Keep the autoinjector in the original carton to protect from light.
The autoinjector should be kept in the refrigerator at 36°F to 46°F (2°C to 8°C).
After removing AIMOVIG from the refrigerator, it can be stored at room temperature between 68°F to 77°F (20°C to 25°C) for up to 7 days.
Throw away AIMOVIG that has been left at room temperature for more than 7 days.
Do not freeze.

Using your AIMOVIG SureClick autoinjector

The needle shield within the white cap of the AIMOVIG autoinjector contains dry natural rubber, which is made from latex. Tell your healthcare provider if you are allergic to latex.
It is important that you do not try to give the injection unless you or your caregiver has received training from your healthcare provider.
Do not use the autoinjector after the expiration date on the label.
Do not shake the autoinjector.
Do not remove the white cap from the autoinjector until you are ready to inject.
Do not freeze or use the autoinjector if it has been frozen.
Do not use the autoinjector if it has been dropped on a hard surface. Part of the autoinjector may be broken even if you cannot see the break. Use a new autoinjector, and call 1-800-77-AMGEN (1-800-772-6436).

Step 1: Prepare

AIMOVIG comes as a single-dose (1 time) prefilled autoinjector. Your healthcare provider will prescribe the dose that is best for you.

Before you inject, always check the label of your single-dose prefilled autoinjector to make sure you have the correct medicine and the correct dose of AIMOVIG.

Remove autoinjector from the carton.

Carefully lift the autoinjector straight up out of the carton.

Leave the autoinjector at room temperature for at least 30 minutes before injecting.

Do not put the autoinjector back in the refrigerator after it has reached room temperature.
Do not try to warm the autoinjector by using a heat source such as hot water or microwave.
Do not leave the autoinjector in direct sunlight.
Do not shake the autoinjector.
Do not remove the white cap from the autoinjector yet.

Inspect the autoinjector.

Make sure the medicine in the window is clear and colorless to slightly yellow.

Do not use the autoinjector if the medicine is cloudy or discolored or contains flakes or particles.
Do not use the autoinjector if any part appears cracked or broken.
Do not use the autoinjector if the autoinjector has been dropped.
Do not use the autoinjector if the white cap is missing or not securely attached.
Do not use the autoinjector if the expiration date printed on the label has passed.

In all cases, use a new autoinjector, and call 1-800-77-AMGEN (1-800-772-6436).

Gather all materials needed for your injection.

Wash your hands thoroughly with soap and water.

On a clean, well-lit work surface, place the:

New autoinjector
Alcohol wipes
Cotton balls or gauze pads
Adhesive bandages
Sharps disposal container
(See “Step 4: Finish”)

Prepare and clean your injection site.

Only use these injection sites:

Your thigh
Stomach area (abdomen), except for a two inch area right around your navel
Outer area of upper arm (only if someone else is giving you the injection)

Clean your injection site with an alcohol wipe. Let your skin dry.

Do not touch this area again before injecting.
Do not inject into areas where the skin is tender, bruised, red, or hard.
Avoid injecting directly into raised, thick, red, or scaly skin patch or lesion, or areas with scars or stretch marks.

Step 2: Get ready

Pull the white cap straight off, only when you are ready to inject. Do not leave the white cap off for more than five minutes. This can dry out the medicine.

It is normal to see a drop of liquid at the end of the needle or green safety guard.

Do not twist or bend the white cap.
Do not put the white cap back onto the autoinjector.
Do not put fingers into the green safety guard.
Do not remove the white cap from the autoinjector until you are ready to inject.

Create a firm surface at the selected injection site (thigh, stomach, or outer areas of the upper arm), by using either the Stretch method or the Pinch method.

Stretch method

Stretch the skin firmly by moving your thumb and fingers in opposite directions, creating an area about two inches wide.

Pinch method

Pinch the skin firmly between your thumb and fingers, creating an area about two inches wide.

Important: It is important to keep skin stretched or pinched while injecting.

Step 3: Inject

Keep holding the stretched or pinched skin. With the white cap off, put the green safety guard on your skin at 90 degrees. The needle is inside the green safety guard. Do not touch the purple start button yet.

Firmly push the autoinjector down onto skin until the autoinjector stops moving.

Important: You must push all the way down but do not touch the purple start button until you are ready to inject.

When you are ready to inject, press the purple start button. You will hear a click.

Keep pushing down on your skin. Then lift your thumb while still holding the autoinjector on your skin. Your injection could take about 15 seconds.

Note: After you remove the autoinjector from your skin, the needle will be automatically covered.

Important: When you remove the autoinjector, if the window has not turned yellow, or if it looks like the medicine is still injecting, this means you have not received a full dose. Call your healthcare provider immediately.

Step 4: Finish

Discard the used autoinjector and the white cap.

Put the used AIMOVIG autoinjector and white cap in a FDA-cleared sharps disposal container right away after use. Do not throw away (dispose of) the SureClick autoinjector in your household trash.

If you do not have a FDA-cleared sharps disposal container, you may use a household container that is:

Made of a heavy-duty plastic
Can be closed with a tight-fitting, puncture-resistant lid, without sharps being able to come out
Upright and stable during use
Leak-resistant
Properly labeled to warn of hazardous waste inside the container

When your sharps disposal container is almost full, you will need to follow your community guidelines for the right way to dispose of your sharps disposal container. There may be state or local laws about how you should throw away used needles and syringes. For more information about safe sharps disposal, and for specific information about sharps disposal in the state that you live in, go to the FDA’s website at: http://www.fda.gov/safesharpsdisposal

Do not reuse the autoinjector.
Do not recycle the autoinjector or sharps disposal container or throw them into household trash.

Important: Always keep the sharps disposal container out of the reach of children.

Examine the injection site.

If there is blood, press a cotton ball or gauze pad on your injection site. Do not rub the injection site. Apply an adhesive bandage if needed.

Commonly asked questions

What will happen if I press the purple start button before I am ready to do the injection on my skin?

Even when you press the purple start button, the injection will only happen when the green safety guard is also pushed into the autoinjector.

Can I move the autoinjector around on my skin while I am choosing an injection site?

It is okay to move the autoinjector around on the injection site as long as you do not press the purple start button. However, if you press the purple start button and the green safety guard is pushed into the autoinjector, the injection will begin.

Can I release the purple start button after I start my injection?

You can release the purple start button, but continue to hold the autoinjector firmly against your skin during the injection.

Will the purple start button pop up after I release my thumb?

The purple start button may not pop up after you release your thumb if you held your thumb down during the injection. This is okay.

What do I do if I did not hear a click after pushing the device down on my skin for 15 seconds?

If you did not hear a click, you can confirm a complete injection by checking that the window has turned yellow.

Whom do I contact if I need help with the autoinjector or my injection?

If you need more information or help, visit www.aimovig.com or call 1-800-77-AMGEN (1-800-772-6436).

This Instructions for Use has been approved by the U.S. Food and Drug Administration.

AIMOVIG^® (erenumab-aooe)

Manufactured by:
Amgen Inc.
One Amgen Center Drive
Thousand Oaks, CA 91320‍-1799 USA
U.S. License No. 1080

30996 Revised: 11/2021 v5

Symbol table

This product contains dry natural rubber

Do not reuse

CAUTION, Prior to use,
read the enclosed
Instructions For Use
for administration
information and
see package insert
for full Prescribing
Information

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